Benzo[a]pyrenediol Epoxide Antikörper
Dieser Maus Monoklonal Antikörper erkennt spezifisch Benzo[a]pyrenediol Epoxide in EIA. Er zeigt eine Reaktivität gegenüber Chemical.
Produktnummer ABIN1105513
Kurzübersicht für Benzo[a]pyrenediol Epoxide Antikörper (ABIN1105513)
Target
Benzo[a]pyrenediol Epoxide (BPDE)
Reaktivität
Chemical
Wirt
Maus
Klonalität
Monoklonal
Applikation
Enzyme Immunoassay (EIA)
Klon
8-00E-011
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Aufreinigung
- Protein G
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C.
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- Benzo[a]pyrenediol Epoxide (BPDE)
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Andere Bezeichnung
- Benzo(a)pyrenediol-Epoxide (BPDE)
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Substanzklasse
- Chemical
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Hintergrund
- A number of chemicals, including polycyclic aromatic hydrocarbons (PAHs), have been shown to bind to DNA. This DNA damage can occur both early and late in the malignant process, thereby acting as an initiator and assisting in the progression of tumors. PAHs are released into the environment following incomplete combustion of organic materials. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Benzo[a]pyrene is a representitive PAH. Antibodies to benzo[a]pyrenediol-epoxide modified DNA (BPDE-DNA) can be used to identify polycyclic aromatic hydrocarbon (PAH)-DNA adducts. Exposure to this group of compounds is believed to be carcinogenic.Synonyms: PAH, polycyclic aromatic hydrocarbon
Target
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